Looking for an audio interface with MIDI ports that makes recording, monitoring, and gear control easier? The right pick can simplify your setup and keep your studio moving fast.
Below, we’ve narrowed the field to 10 practical options for musicians, podcasters, and home studio users who want solid audio performance plus dependable MIDI connectivity.
Best 10 Audio Interface with Midi Ports Picks for 2026
Studio Hub for Multi-Device Rigs
Focusrite Scarlett 4i4 4th Gen
- MIDI I/O plus 4-in/4-out layout
- 120dB dynamic range, 24-bit/192kHz
- Auto Gain, Clip Safe, Air mode
Best For: Musicians building a compact studio with synths and MIDI gear
Portable Budget Pick
PreSonus AudioBox 96 25th Anniversary
- MIDI I/O with two mic preamps
- USB bus-powered for portability
- Includes Studio One Artist and Ableton Live Lite
Best For: Portable, beginner-friendly recording with basic MIDI support
MIDI Cable for Direct Keyboard Connection
- 1 in / 1 out USB-C MIDI interface cable
- Plug-and-play on supported systems
- LED indicators help monitor MIDI data
Best For: MIDI-only keyboard and synth connections to a computer
Compact Creator Interface
Focusrite Scarlett 2i2 4th Gen
- 120dB dynamic range, 24-bit/192kHz
- Auto Gain, Clip Safe, Air mode
- Includes software and plugin bundle
Best For: Solo recording where onboard MIDI is not required
MOTU pick for flexible home studios
Motu M4 4x4 USB-C Audio Interface
- 4x4 USB-C interface with MIDI I/O
- Two mic preamps and hardware monitoring
- Mac, PC, and iOS compatibility
Best For: Home studios and creators who need MIDI I/O with low-latency monitoring
Mackie choice for compact MIDI recording
Onyx Producer 2X2 USB Audio Interface with MIDI
- 2-in/2-out interface with MIDI I/O
- Two Onyx preamps with phantom power
- Bus-powered with zero-latency monitoring
Best For: Small studios and mobile recording with MIDI gear
M-Audio budget-friendly beginner pick
M-AUDIO M-Track Duo USB Audio Interface
- Two combo inputs for vocals and instruments
- Zero-latency monitoring with USB/Direct switch
- No MIDI I/O listed in the notes
Best For: Beginners who need a portable recording and streaming interface
Studio-Ready 4x4 Pick
Behringer U-PHORIA UMC404HD 4x4 USB Audio/MIDI Interface
- 4x4 USB audio with 1x MIDI I/O
- 24-bit/192 kHz recording support
- 4 MIDAS-designed preamps with phantom power
Best For: home recordists who need MIDI and multitrack inputs
Portable Creator Choice
Synido USB-C Audio Interface for Recording
- Compact 2x2 USB-C interface
- Three monitoring modes for flexible use
- 48V phantom power and easy setup
Best For: streamers and podcasters needing a portable interface
Compact Routing Pick
MAONO PS22 Lite USB Audio Interface
- 24-bit/192 kHz recording and 106 dB dynamic range
- Dedicated instrument input with 48V phantom power
- ProStudio Routing Software with ASIO support
Best For: beginners and streamers who want simple routing
Studio Hub for Multi-Device Rigs – Focusrite Scarlett 4i4 4th Gen
If you want an audio interface with midi ports that can sit at the center of a small studio, the Scarlett 4i4 4th Gen is built for that role. It combines 2 mic preamps, 2 Hi-Z inputs, 4 line inputs, 4 line outputs, and MIDI I/O, so it can handle mics, guitars, synths, and drum machines in one setup.
Best For: Musicians who need a compact interface with MIDI I/O and enough I/O for a growing home studio.
Pros:
- Includes MIDI In/Out alongside 4-in/4-out connectivity.
- Offers 120dB dynamic range and 24-bit/192kHz recording.
- Auto Gain and Clip Safe help keep takes clean and usable.
- Air mode adds presence and harmonic drive to vocals and guitars.
Cons:
- More interface than you need if you only record one mic and one instrument.
- Requires external USB-C power supply in the box.
Overall, the 4i4 is the most flexible option here for a musician who wants real expansion room without moving up to a larger rack-style interface.
Portable Budget Pick – PreSonus AudioBox 96 25th Anniversary
The PreSonus AudioBox 96 is a practical audio interface with midi ports for users who want a simple, portable recording setup. Its two mic preamps, two instrument inputs, and MIDI I/O make it easy to connect a small keyboard-based rig, while USB bus power keeps the setup mobile.
Best For: Beginner and portable recording setups that need MIDI I/O without a lot of extra complexity.
Pros:
- Includes MIDI I/O and two high-headroom instrument inputs.
- USB bus-powered design is convenient for travel or desktop use.
- 24-bit/96kHz converters are solid for straightforward recording.
- Comes with Studio One Artist, Ableton Live Lite, and Studio Magic Plug-In suite.
Cons:
- Only offers two channels, so it is not ideal for larger sessions.
- Max sample rate is 96kHz, lower than some newer interfaces.
This is a good value choice if you want a basic, dependable interface that can also connect MIDI hardware without requiring a separate power supply.
MIDI Cable for Direct Keyboard Connection – LEKATO MIDI to USB C
If your search is specifically for an audio interface with midi ports, the LEKATO cable is a different kind of solution: it is a USB-C MIDI interface cable for connecting keyboards, synths, drum pads, and similar gear to a computer. It is designed for simple MIDI editing and recording, with plug-and-play operation and built-in status LEDs.
Best For: Players who need a straightforward USB-C MIDI connection rather than a full audio recording interface.
Pros:
- 1 in / 1 out design supports standard MIDI devices.
- Plug-and-play setup with no special drivers required on supported systems.
- LED indicators make MIDI power and data flow easy to monitor.
- Works with Windows and Mac systems, plus iPad compatibility is noted.
Cons:
- Does not record audio like a traditional interface.
- Only covers basic 1-in/1-out MIDI connections.
For MIDI-only workflows, this is a simple and affordable way to link hardware to your computer, but it is not a substitute for a full audio interface.
Compact Creator Interface – Focusrite Scarlett 2i2 4th Gen
The Scarlett 2i2 4th Gen is a compact audio interface for creators who want Focusrite’s latest sound and workflow features in a simple 2-channel design. It is a strong pick if you are comparing an audio interface with midi ports but do not actually need MIDI on the unit, since this model focuses on mic and instrument recording with modern tools like Auto Gain and Clip Safe.
Best For: Solo musicians and podcasters who want a clean 2-input interface and do not need onboard MIDI I/O.
Pros:
- 120dB dynamic range and 24-bit/192kHz support.
- Auto Gain and Clip Safe simplify level setting and protect takes.
- Air mode adds presence and harmonic drive to vocals and guitars.
- Includes recording software and the Hitmaker Expansion plugin bundle.
Cons:
- No MIDI I/O on the interface itself.
- Only two channels, so it is less flexible than 4-input models.
This is the best fit if your priority is high-quality two-channel recording in a small package, but you should look elsewhere if onboard MIDI ports are a must.
MOTU pick for flexible home studios – Motu M4 4×4 USB-C Audio Interface
If you want an audio interface with midi ports that also feels ready for everyday recording, the MOTU M4 is a strong all-around option. It combines 4×4 USB-C connectivity, MIDI I/O, two microphone preamps, hardware monitoring, and a front-panel LCD screen, making it practical for music production, podcasting, and simple mobile setups.
Best For: Home studios, podcasters, and musicians who want MIDI I/O plus low-latency monitoring in a compact interface.
Pros:
- Includes MIDI I/O alongside 4×4 USB-C audio connectivity
- Two microphone preamps and hardware monitoring support practical recording sessions
- LCD screen helps with quick level checking
- Mac, PC, and iOS compatibility adds flexibility
Cons:
- No included operating system is listed
- Only two mic preamps, so larger input needs may require a bigger unit
Overall, the M4 stands out as a versatile pick for users who need MIDI support without giving up straightforward recording and monitoring features. It looks especially useful for creators who want one interface to handle multiple day-to-day tasks.
Mackie choice for compact MIDI recording – Onyx Producer 2X2 USB Audio Interface with MIDI
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonThe Mackie Onyx Producer 2X2 is a compact audio interface with midi ports built for simple, high-quality recording. It offers 2-in/2-out 24-bit/192kHz performance, MIDI I/O, two Onyx mic preamps, and zero-latency direct monitoring, so it fits well in small studio or mobile recording setups.
Best For: Small studios and mobile musicians who want MIDI I/O, strong preamps, and bus-powered convenience.
Pros:
- Includes MIDI I/O for connecting compatible gear
- Two Onyx mic preamps with phantom power support condenser mics
- Zero-latency direct monitoring with dedicated outputs
- Bus-powered USB 2.0 design is easy for portable use
Cons:
- 2-in/2-out layout is limited for larger recording sessions
- Designed around PC, iOS, and macOS use rather than broad studio expansion
For users who need MIDI without a bulky interface, the Producer 2X2 keeps the feature set focused and portable. Its mix of high-resolution recording and straightforward monitoring makes it a sensible pick for lean setups.
M-Audio budget-friendly beginner pick – M-AUDIO M-Track Duo USB Audio Interface
The M-AUDIO M-Track Duo is a simple USB audio interface for basic recording, streaming, and podcasting, but it does not include midi ports. It focuses on everyday essentials like two combo XLR/Line/Instrument inputs, transparent Crystal Preamps, zero-latency monitoring, and a compact design that works with Mac, PC, and mobile devices.
Best For: Beginners who want a portable two-input interface for vocals, instruments, and streaming.
Pros:
- Two combo XLR/Line/Instrument inputs handle multiple source types
- USB/Direct switch supports zero-latency monitoring
- Works with Mac, PC, Android, and iOS devices
- Includes MPC Beats software for getting started
Cons:
- No MIDI I/O is listed in the supplied notes
- 48kHz maximum sample rate is lower than some higher-end interfaces
This is a solid entry-level interface if your main needs are recording and streaming rather than MIDI control. Its feature set is easy to understand, making it a practical choice for first-time buyers.
Studio-Ready 4×4 Pick – Behringer U-PHORIA UMC404HD 4×4 USB Audio/MIDI Interface
If you want an audio interface with midi ports for a small studio setup, the Behringer U-PHORIA UMC404HD gives you 4×4 USB audio, one MIDI I/O, and 24-bit/192 kHz recording. It is built for recording microphones and instruments, and its MIDAS-designed preamps make it a practical choice when you need straightforward multitrack capture with low-latency monitoring.
Best For: Home recordists who want 4 inputs, MIDI connectivity, and solid preamps in one rugged unit.
Pros:
- 4×4 USB audio plus 1x MIDI I/O for flexible tracking
- 24-bit/192 kHz resolution for high-quality recording
- Four MIDAS-designed mic preamps with +48V phantom power
- Metal chassis built for durability
Cons:
- Designed around USB 2.0 rather than newer connection standards
- Best suited to users who need a more traditional desktop interface
Overall, this is a dependable option if your priority is recording multiple sources and integrating MIDI in one box. The feature set is especially attractive for musicians who want a sturdy interface that can handle common DAWs and serious home-studio use.
Portable Creator Choice – Synido USB-C Audio Interface for Recording
This USB-C audio interface is a practical pick if you want a compact audio interface with midi ports-style versatility in a lightweight creator setup, though its supplied notes focus on audio features rather than actual MIDI connectivity. It offers 2×2 recording, 24-bit/48 kHz conversion, and three monitoring modes, making it a useful fit for streaming, podcasting, and simple home recording.
Best For: Streamers and podcasters who want a small, easy-to-use interface for voice and instrument recording.
Pros:
- Compact 2×2 interface with USB-C connectivity
- 24-bit/48 kHz sound with low-latency performance
- Three monitoring modes: Stereo, Mix, and USB
- 48V phantom power and XLR/6.35mm compatibility
Cons:
- No MIDI ports are mentioned in the supplied product details
- 48 kHz maximum sample rate is lower than some studio-focused options
For creators who value portability and simple controls, this interface keeps the workflow approachable. It is best viewed as a compact recording and streaming tool rather than a full-featured MIDI hub.
Compact Routing Pick – MAONO PS22 Lite USB Audio Interface
The MAONO PS22 Lite is a compact option if you are shopping for an audio interface with midi ports for a creator setup, but its supplied notes focus on audio and routing features rather than built-in MIDI connectors. It delivers 24-bit/192 kHz recording, a dedicated instrument input, and ProStudio Routing Software for low-latency streaming and flexible channel control.
Best For: Beginners, streamers, and musicians who want a compact interface with strong routing tools.
Pros:
- 24-bit/192 kHz recording with 106 dB dynamic range
- 48V phantom power and up to 56 dB preamp gain
- Dedicated instrument input for guitar and vocal recording
- Includes ProStudio Routing Software with ASIO support
Cons:
- No MIDI ports are listed in the provided details
- Best suited to compact setups rather than larger multi-input rigs
As a small desktop interface, the PS22 Lite stands out for its routing software and simple mode switching. It is a sensible pick if you want an easy recording workflow and do not need the broader I/O count of a larger interface.
How We Picked the Best Audio Interface with Midi Ports
We focused on interfaces that offer a useful mix of audio quality, MIDI connectivity, input/output flexibility, and everyday reliability. For an Audio Interface with Midi Ports, that means checking whether the device can handle your microphones, instruments, keyboards, and controller workflow without forcing awkward adapters or limiting expansion.
We also looked at sample-rate support, preamp quality, direct monitoring, bus-powered convenience, driver reputation, and how well each model fits common use cases like home recording, streaming, and small-project studio work.
Quick Comparison
The best choice depends on how you record. Compact 2-in/2-out models are ideal for simple vocal or guitar sessions, while 4×4 interfaces give you more room for mics, instruments, and external MIDI hardware. If your setup centers on a keyboard, synth, or drum machine, prioritize clear MIDI input and output plus enough physical I/O to avoid constant re-patching.
USB-C models are especially appealing for newer computers, but compatibility and stable drivers matter more than connector type alone. A good MIDI interface should also make routing straightforward, so you can record or sequence hardware without extra technical friction.
Key Buying Factors for an Audio Interface with Midi Ports
Audio and MIDI I/O Count
Match the number of inputs and outputs to your real workflow. Solo artists may only need one or two mic/instrument inputs, while multi-source recording or hardware integration often benefits from extra line outs and true MIDI in/out ports.
Preamp Quality and Monitoring
Clean preamps help keep recordings quiet and detailed, especially when using dynamic microphones or low-output instruments. Low-latency direct monitoring is also important if you want to track vocals or instruments without distracting delay.
Computer and Device Compatibility
Make sure the interface works smoothly with your operating system and DAW. Some devices are better suited to Windows or macOS, and others are designed for simple plug-and-play use with laptops, tablets, or mobile recording rigs.
Build, Power, and Workflow
If you travel or record in tight spaces, compact size and bus power can matter a lot. If your setup is more permanent, larger front-panel controls and additional routing options may be worth the extra space.
Who Should Buy Which Audio Interface with Midi Ports?
Choose a compact interface if you mainly record vocals, guitar, or a single instrument at a time. Choose a 4×4 model if you want more routing flexibility, better hardware integration, or a studio setup that may grow later. If MIDI is central to your workflow, prioritize an Audio Interface with Midi Ports that has both dependable connectivity and enough audio channels to keep your sessions efficient.
For streamers and podcasters, simple controls, fast setup, and dependable monitoring may matter more than extensive I/O. For musicians using keyboards, synths, or external sequencers, the best value usually comes from a model that balances clear MIDI support with stable audio performance and low-latency operation.